Novel amphiphilic linear polymer/dendrimer block copolymer: Synthesis of poly(2-methyl-2-oxazoline)-block-poly(amido amine) dendrimer

Novel linear polymer/dendrimer block copolymers, poly(2‐methyl‐2‐oxazoline)‐block‐poly(amido amine) dendrimers (water‐soluble full‐generation type 4 (G = 4.0 and 5.0) and amphiphilic half‐generation type 5 (G = 3.5, 4.5, and 5.5)), were synthesized by divergent‐growth dendrimer construction with ω‐ethylenediamine‐terminated poly(2‐methyl‐2‐oxazoline), which was prepared by living ring‐opening polymerization of 2‐methyl‐2‐oxazoline. Assembly of the amphiphilic dendrimer‐based block copolymer (G = 5.5) was investigated by surface tension measurements (critical micelle concentration, 0.49 wt.‐%) and by small‐angle neutron scattering analysis (spherical particles; assembled number, ca. 103).