Effect of hematoporphyrin derivative 2 on estrogen receptors in experimental mammary tumors

This study reports the effect of hematoporphyrin derivative 2 (HPD2) on estrogen receptors (ER) in the animal model used to develop the clinical ER assay. Fifty 200‐g female Sprague‐Dawley rats were given 20 mg of dimethylbenzanthracene by gastric intubation. Spontaneous mammary tumors occurred in 3...

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Veröffentlicht in:	Lasers in surgery and medicine 1987, Vol.7 (3), p.280-282
Hauptverfasser:	Lanzafame, Raymond J., Rogers, David W., Naim, John O., Herrera, H. Raul, Hinshaw, J. Raymond
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene Animal tumors. Experimental tumors Animals Antineoplastic Agents - pharmacology Biological and medical sciences cancer dihematoporphyrin ether dimethylbenzanthracene estrogen receptor analysis Experimental genital and mammary tumors Female Hematoporphyrin Derivative Hematoporphyrin Photoradiation Hematoporphyrins - pharmacology Mammary Neoplasms, Experimental - chemically induced Mammary Neoplasms, Experimental - drug therapy Medical sciences porphyrins Rats Rats, Inbred Strains Receptors, Estrogen - drug effects rodents tumor markers Tumors
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