Pepsinogen/Proton Pump Co‐Expression in Barrett's Esophageal Cells Induces Cancer‐Associated Changes

Educational Objective At the conclusion of this presentation, participants should better understand the carcinogenic potential of pepsin and proton pump expression in Barrett's esophagus. Objective Barrett's esophagus (BE) is a well‐known risk factor for esophageal adenocarcinoma (EAC). Ga...

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Veröffentlicht in:	The Laryngoscope 2023-01, Vol.133 (1), p.59-69
Hauptverfasser:	Stabenau, Kaleigh A., Samuels, Tina L., Lam, Tina K., Mathison, Angela J., Wells, Clive, Altman, Kenneth W., Battle, Michele A., Johnston, Nikki
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - metabolism Barrett Esophagus - complications Barrett's esophagus Carcinogenesis differential gene expression esophageal adenocarcinoma Esophageal Neoplasms - pathology gastric acid Gastroesophageal reflux disease Humans pepsin Pepsin A - metabolism pepsinogen Pepsinogen A - metabolism Proton Pump Inhibitors Proton Pumps RNA sequencing Tumor Microenvironment
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