In vivo ethane production in vitamin E-deficient rats with DMH-induced colon cancer

The effect of both a vitamin E‐deficient and a high polyunsaturated fat (PUFA) diet was tested on rats injected with the colon carcinogen 1,2‐dimethylhydrazine (DMH). In vivo lipid peroxidation was monitored by measuring exhaled ethane from the animals. Higher mean weights were found in animals fed...

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Veröffentlicht in:	Journal of surgical oncology 1987-10, Vol.36 (2), p.142-147
Hauptverfasser:	Slater, Gary, Kang, Jae, Cohen, Gerald, Szporn, Arnold, Aufses Jr, Arthur H.
Format:	Artikel
Sprache:	eng
Schlagworte:	1,2-Dimethylhydrazine Animals Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Chemical agents colon cancer Colonic Neoplasms - chemically induced Colonic Neoplasms - metabolism Dimethylhydrazines - toxicity DMH ethane Ethane - metabolism Fatty Acids, Unsaturated - administration & dosage lipid peroxidation Lipid Peroxides - metabolism Male Medical sciences polyunsaturated fat Rats Rats, Inbred Strains Tumors vitamin E Vitamin E Deficiency - metabolism
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