Synthesis and Characterization of Fluorescent Surfactants for Studying the Penetration of Cosmetic Surfactants on the Skin
Surfactants are one of the important ingredients of cosmetics. However, their penetration and penetration‐promoting behavior in the skin has not been well understood. Aiming to explore the surfactant penetration in skin, a novel fluorescent surfactant F‐C16, based on sodium fluorescein, was synthesi...
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| Veröffentlicht in: | Journal of surfactants and detergents 2020-09, Vol.23 (5), p.937-943 |
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| container_title | Journal of surfactants and detergents |
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| creator | Kong, Shuai Shen, Chong Luo, Yulu Meng, Qin |
| description | Surfactants are one of the important ingredients of cosmetics. However, their penetration and penetration‐promoting behavior in the skin has not been well understood. Aiming to explore the surfactant penetration in skin, a novel fluorescent surfactant F‐C16, based on sodium fluorescein, was synthesized in this paper. F‐C16 has a fluorescence maxima (λem) of around 530 nm, and its fluorescence increased with the polarity of solvent. It possesses good emulsifying properties and low cytotoxicity. Hence, it can be used as a quickly detected indicator for surfactants in cosmetics. As demonstrated by this fluorescent surfactant, it was found that the surfactants can penetrate well into skin and cells. It seems that surfactants in cosmetics can enter the cells and reach the dermal layer of skin. |
| doi_str_mv | 10.1002/jsde.12416 |
| format | Article |
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However, their penetration and penetration‐promoting behavior in the skin has not been well understood. Aiming to explore the surfactant penetration in skin, a novel fluorescent surfactant F‐C16, based on sodium fluorescein, was synthesized in this paper. F‐C16 has a fluorescence maxima (λem) of around 530 nm, and its fluorescence increased with the polarity of solvent. It possesses good emulsifying properties and low cytotoxicity. Hence, it can be used as a quickly detected indicator for surfactants in cosmetics. As demonstrated by this fluorescent surfactant, it was found that the surfactants can penetrate well into skin and cells. It seems that surfactants in cosmetics can enter the cells and reach the dermal layer of skin.</description><identifier>ISSN: 1097-3958</identifier><identifier>EISSN: 1558-9293</identifier><identifier>DOI: 10.1002/jsde.12416</identifier><language>eng</language><publisher>Hoboken, USA: John Wiley & Sons, Inc</publisher><subject>Cell culture ; Chemical synthesis ; Emulsifying properties ; Fluorescent surfactant ; Penetration ; Skin barrier</subject><ispartof>Journal of surfactants and detergents, 2020-09, Vol.23 (5), p.937-943</ispartof><rights>2020 AOCS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2736-10e9ed2e85cde6fa07f94e8e1e33f21b39382866b757ecc903a8f6e6776aa0973</citedby><cites>FETCH-LOGICAL-c2736-10e9ed2e85cde6fa07f94e8e1e33f21b39382866b757ecc903a8f6e6776aa0973</cites><orcidid>0000-0001-5518-4642</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjsde.12416$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjsde.12416$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,778,782,1414,27911,27912,45561,45562</link.rule.ids></links><search><creatorcontrib>Kong, Shuai</creatorcontrib><creatorcontrib>Shen, Chong</creatorcontrib><creatorcontrib>Luo, Yulu</creatorcontrib><creatorcontrib>Meng, Qin</creatorcontrib><title>Synthesis and Characterization of Fluorescent Surfactants for Studying the Penetration of Cosmetic Surfactants on the Skin</title><title>Journal of surfactants and detergents</title><description>Surfactants are one of the important ingredients of cosmetics. However, their penetration and penetration‐promoting behavior in the skin has not been well understood. Aiming to explore the surfactant penetration in skin, a novel fluorescent surfactant F‐C16, based on sodium fluorescein, was synthesized in this paper. F‐C16 has a fluorescence maxima (λem) of around 530 nm, and its fluorescence increased with the polarity of solvent. It possesses good emulsifying properties and low cytotoxicity. Hence, it can be used as a quickly detected indicator for surfactants in cosmetics. As demonstrated by this fluorescent surfactant, it was found that the surfactants can penetrate well into skin and cells. It seems that surfactants in cosmetics can enter the cells and reach the dermal layer of skin.</description><subject>Cell culture</subject><subject>Chemical synthesis</subject><subject>Emulsifying properties</subject><subject>Fluorescent surfactant</subject><subject>Penetration</subject><subject>Skin barrier</subject><issn>1097-3958</issn><issn>1558-9293</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kEtLAzEUhYMoWKsbf0HWwtRk0sljKWPrg4LC6HpIMzc2tc1IkkGmv96pFcGNq3vgfOfAPQhdUjKhhOTX69jAhOZTyo_QiBaFzFSu2PGgiRIZU4U8RWcxrgeWTotihHZV79MKootY-waXKx20SRDcTifXetxaPN90bYBowCdcdcEOvvYpYtsGXKWu6Z1_w0MHfgYPKfzmyjZuITnzJzRYe7R6d_4cnVi9iXDxc8fodT57Ke-zxdPdQ3mzyEwuGM8oAQVNDrIwDXCribBqChIoMGZzumSKyVxyvhSFAGMUYVpaDlwIrvXwNRujq0OvCW2MAWz9EdxWh76mpN6vVu9Xq79XG2B6gD_dBvp_yPqxup0dMl_rMnJ3</recordid><startdate>202009</startdate><enddate>202009</enddate><creator>Kong, Shuai</creator><creator>Shen, Chong</creator><creator>Luo, Yulu</creator><creator>Meng, Qin</creator><general>John Wiley & Sons, Inc</general><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0001-5518-4642</orcidid></search><sort><creationdate>202009</creationdate><title>Synthesis and Characterization of Fluorescent Surfactants for Studying the Penetration of Cosmetic Surfactants on the Skin</title><author>Kong, Shuai ; Shen, Chong ; Luo, Yulu ; Meng, Qin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2736-10e9ed2e85cde6fa07f94e8e1e33f21b39382866b757ecc903a8f6e6776aa0973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Cell culture</topic><topic>Chemical synthesis</topic><topic>Emulsifying properties</topic><topic>Fluorescent surfactant</topic><topic>Penetration</topic><topic>Skin barrier</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kong, Shuai</creatorcontrib><creatorcontrib>Shen, Chong</creatorcontrib><creatorcontrib>Luo, Yulu</creatorcontrib><creatorcontrib>Meng, Qin</creatorcontrib><collection>CrossRef</collection><jtitle>Journal of surfactants and detergents</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kong, Shuai</au><au>Shen, Chong</au><au>Luo, Yulu</au><au>Meng, Qin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis and Characterization of Fluorescent Surfactants for Studying the Penetration of Cosmetic Surfactants on the Skin</atitle><jtitle>Journal of surfactants and detergents</jtitle><date>2020-09</date><risdate>2020</risdate><volume>23</volume><issue>5</issue><spage>937</spage><epage>943</epage><pages>937-943</pages><issn>1097-3958</issn><eissn>1558-9293</eissn><abstract>Surfactants are one of the important ingredients of cosmetics. 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| ispartof | Journal of surfactants and detergents, 2020-09, Vol.23 (5), p.937-943 |
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| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Cell culture Chemical synthesis Emulsifying properties Fluorescent surfactant Penetration Skin barrier |
| title | Synthesis and Characterization of Fluorescent Surfactants for Studying the Penetration of Cosmetic Surfactants on the Skin |
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