Mechanism of the Enhancement Effect of n‐Octyl‐β‐D‐thioglucoside on the Transdermal Penetration of Fluorescein lsoiliocyanate-Labeled Dextrans and the Molecular Weight Dependence of Water-Soluble Penetrants through Stripped Skin

To clarify the mechanism of the enhancing effect ofn‐octyl‐β‐D‐thioglucoside (OTG), which acts as a potent enhancer for skin penetration of peptides and water‐soluble penetrants, the in vitro penetration of macromolecules [fluorescein isothiocyanate‐labeled dextrans (FTIC‐dextrans)] was evaluated wi...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1994-12, Vol.83 (12), p.1676-1681
Hauptverfasser:	Ogiso, Taro, Paku, Tsuyoshi, Iwaki, Masahiro, Tanino, Tadatoshi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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