Transdermal lontophoretic Peptide Delivery: In Vitro and In Vivo Studies with Luteinizing Hormone Releasing Hormone

Protein and peptide drugs are not orally active. Their large molecular size and charged character make them poor candidates for passive transdermal delivery. With an applied electromotive force, these drugs can be forced through the skin to be absorbed by the systemic circulation. The present study...

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Veröffentlicht in:Journal of pharmaceutical sciences 1993-03, Vol.82 (3), p.240-243
Hauptverfasser: Heit, Mark C., Williams, Patrick L., Chang, Shao K., Riviere, Jim E., Jayes, Friederike L.
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Sprache:eng
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