Atropine Absorption after Intramuscular Administration with 2-Pralidoxime Chloride by Two Automatic Injector Devices

Compared with manual intramuscular injection, automatic injector delivery substantially enhances drug absorption rate. We examined the effect of two types of automatic injector delivery of two drugs which are components of the standard antidote to anticholinesterase poisoning and which have been pre...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1989-09, Vol.78 (9), p.728-731
Hauptverfasser:	Friedl, Karl E., Hannan, Charles J., Schadler, Paul W., Jacob, Willis H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Accommodation, Ocular - drug effects Adult Atropine - administration & dosage Atropine - pharmacokinetics Atropine - pharmacology Biological and medical sciences Cholinergic system Creatine Kinase - antagonists & inhibitors Heart Rate - drug effects Humans Injections, Intramuscular - instrumentation Male Medical sciences Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Pharmacology. Drug treatments Pralidoxime Compounds - pharmacology Salivation - drug effects
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