Cardiovascular Effects of Digoxin—Phenelzine Interaction in Rabbits

The potential toxicity of combining phenelzine, an MAO inhibitor, and digoxin, a cardiac glycoside, was studied in rabbits. Cardiovascular responses following concurrent administration of these drugs and the administration of these drugs 20 and 60min. apart, respectively, revealed that phenelzine an...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1973-11, Vol.62 (11), p.1876-1878
Hauptverfasser:	Bohrman, Jeffrey S., Thompson, Emmanuel B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arrhythmias, Cardiac - chemically induced Blood Pressure - drug effects Digoxin - antagonists & inhibitors Digoxin - pharmacology Digoxin-phendzine interactions-cardiovascular effects in rabbits Digoxin-phenelzine interactions cardiovascular effects in rabbits, dose-time relationships digoxin-phenelzine-cardiovascular effects in rabbits Digoxin‐phendzine interactions—cardiovascular effects in rabbits, dose‐time relationships dose-time relationships Drug Interactions Drug interactions digoxin-phenelzine in rabbits Female Heart Rate - drug effects Interactions Interactions, digoxin-phenelzine—cardiovascular effects in rabbits, dose-time relationships Phenelzine - pharmacology Phenelzine-digoxin interactions-cardiovascular effects in rabbits Phenelzine-digoxin interactions—cardiovascular effects in rabbits, dose -time relationships Rabbits Time Factors
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