Preliminary Pharmacology of Ellagic Acid From Juglans nigra (Black Walnut)

A crystalline compound was isolated from Juglans nigra which by comparison with the known compound was found to be ellagic acid. The ellagic acid injected (i.p.) produced significant sedation, ataxia, potentiated sodium pentobarbital sleeping time, and protected mice from death after electroconvulsi...

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Veröffentlicht in:	Journal of pharmaceutical sciences 1968-10, Vol.57 (10), p.1728-1732
Hauptverfasser:	Bhargava, U.C., Westfall, B.A., Siehr, D.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticonvulsants - pharmacology Ataxia - chemically induced Benzopyrans - pharmacology Blood Pressure - drug effects Duodenum - drug effects Electroshock - adverse effects Ellagic acid-Juglans nigra Female Heart Rate - drug effects Hypnotics and Sedatives - pharmacology Hypotension - chemically induced IR spectrophotometry-identity Male Mice Nuts Pentobarbital - pharmacology Pharmacologic screening-ellagic acid Rats Respiration - drug effects Shock - mortality Uterus - drug effects UV spectrophotometry-identity
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