$Effects of short-term Cyclosporin-A on biomechanical properties of intact and fractured bone in the rat$

Effects of short-term Cyclosporin-A on biomechanical properties of intact and fractured bone in the rat

Cyclosporin‐A is a new immunosuppressant drug being used widely for solid organ transplantation. The systemic effects of Cyclosporin‐A on the skeletal system have not previously been defined. This study examined the effects of Cyclosporin‐A on biomechanical properties of intact bone and fracture rep...

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Veröffentlicht in:	Journal of orthopaedic research 1985, Vol.3 (1), p.96-100
Hauptverfasser:	Warren, Steven B., Pelker, Richard R., Friedlaender, Gary E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Biomechanical Phenomena Biomechanics Bone and Bones - drug effects Bone and Bones - physiology Cyclosporin-A Cyclosporins - pharmacology Cyclosporins - therapeutic use Drug Evaluation, Preclinical Female Femoral Fractures - drug therapy Femoral Fractures - physiopathology Fracture Fixation, Intramedullary Fracture repair Immunomodulators Immunosuppression Intact bone turnover Medical sciences Pharmacology. Drug treatments Rats Rats, Inbred Strains Time Factors Torsion-testing Wound Healing - drug effects
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