Syntheses of [6-14C] and [5-carboxy, 6-14C2]nitrendipine

[6‐14C]Nitrendipine synthesis started from barium[14]carbonate, which was converted to [1‐14C]acetyl chloride. The acid chloride was condensed with Meldrum's acid (2,2‐dimethyl‐1,3‐dioxane‐4,6‐dione). The resulting intermediate was treated with boiling methanol to give methyl [3‐14C]acetoacetat...

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Bibliographische Detailangaben

Veröffentlicht in:	Journal of labelled compounds & radiopharmaceuticals 1989-04, Vol.27 (4), p.457-463
Hauptverfasser:	Maul, W., Scherling, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	calcium antagonist carbon-14 Knövenagel condensation Meldrum's acid Michael addition
Online-Zugang:	Volltext
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