Synthesis of carbon-14 labeled 4-bromo-2,7-dimethoxy-3H-phenothiazin-3-one

Two different syntheses of (5), one labeled with carbon‐14 in the quinonoid ring and the other in the phenyl ring are described. Treatment of p‐[U‐14C]benzoquinone with 2‐amino‐5‐methoxy benzenethiol yielded (7), which was methoxylated to provide a mixture of isomers (4a) and (8). Separation of isom...

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Veröffentlicht in:	Journal of labelled compounds & radiopharmaceuticals 1987-01, Vol.24 (1), p.97-105
Hauptverfasser:	Prakash, S. R., Ellsworth, R. L., Mertel, H. E.
Format:	Artikel
Sprache:	eng
Schlagworte:	10a-14C]phenothiazin-3-one 4-bromo-2 4‐bromo‐2,7‐dimethoxy‐3H‐[U‐1,2,3,4,4a,10a‐14C]phenothiazin‐3‐one 4‐bromo‐2,7‐dimethoxy‐3H‐[U‐5a,6,7,8,9,9a‐14C]phenothiazin‐3‐one 7-dimethoxy-3H-[U-1 7-dimethoxy-3H-[U-5a 9a-14C]phenothiazin-3-one leukotriene biosynthesis inhibitor P-[U-14C]anisidine P-[U-14C]benzoquinone
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