Synthesis of the lipid peroxidation product 4‐hydroxy‐2(E)‐nonenal with 13 C stable isotope incorporation
The aim of this work was to synthesize 13 C internal standards for the quantification of 4‐hydroxy‐2(E)‐nonenal (HNE), a lipid peroxidation product, and of the etheno‐adducts possibly formed by HNE damage to DNA nucleobases. We designed an eight‐step synthesis starting from ethyl 2‐bromoacetate and...
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Veröffentlicht in: | Journal of labelled compounds & radiopharmaceuticals 2008-02, Vol.51 (2), p.87-92 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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