Synthesis of carbon-14-labeled isotopomer of 6-(4-methanesulfonylphenyl)-5-[4-(2-piperidin-1-yl-ethoxy)phenoxy]-naphthalen-2-ol HCL salt (LY2066948-[14C] HCL salt)

Carbon‐14‐labeled 6‐(4‐methanesulfonylphenyl)‐5‐[4‐(2‐piperidin‐1‐yl‐ethoxy)phenoxy]naphthalen‐2‐ol, a novel selective estrogen receptor modulator (SERM) was synthesized. The key component, 6‐methoxy‐1‐tetralone‐[carbonyl‐14C], was synthesized from 3‐(3‐methoxyphenyl)‐propionic acid via an intra‐mol...

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Veröffentlicht in:	Journal of labelled compounds & radiopharmaceuticals 2007-07, Vol.50 (8), p.706-710
Hauptverfasser:	Kuo, Fengjiun, Clodfelter, Dean K., Priest, Tamara R.
Format:	Artikel
Sprache:	eng
Schlagworte:	6-methoxy-1-tetralone-[1-14C] Biological and medical sciences Contrast media. Radiopharmaceuticals LY2066948-[14C] Medical sciences Pharmacology. Drug treatments SERM GYN
Online-Zugang:	Volltext
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