Synthesis of Some New Heterocycles Derived from Ethyl 7‐Amino‐3‐(3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazolin‐4‐yl)‐5‐aryl‐5 H ‐thiazolo[3,2‐ a ]pyrimidine‐6‐carboxylate of Biological Importance

Ethyl 7‐amino‐3‐(3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazolin‐4‐yl)‐5‐aryl‐5 H ‐thiazolo[3,2‐ a ]pyrimidine‐6‐carboxylate was synthesized by the reaction of 4‐(2‐aminothiazol‐4‐yl)‐3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazoline with arylidene ethyl cyanoacetate and it transformed to related fused heterocyclic systems...

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Veröffentlicht in:Journal of heterocyclic chemistry 2013-03, Vol.50 (2), p.179-187
Hauptverfasser: Youssef, Mohamed Salah K., Abbady, Mohamed S., Ahmed, Ragaa A., Omar, Ahmed A.
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container_title Journal of heterocyclic chemistry
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creator Youssef, Mohamed Salah K.
Abbady, Mohamed S.
Ahmed, Ragaa A.
Omar, Ahmed A.
description Ethyl 7‐amino‐3‐(3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazolin‐4‐yl)‐5‐aryl‐5 H ‐thiazolo[3,2‐ a ]pyrimidine‐6‐carboxylate was synthesized by the reaction of 4‐(2‐aminothiazol‐4‐yl)‐3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazoline with arylidene ethyl cyanoacetate and it transformed to related fused heterocyclic systems via reaction with various reagents. The biological activities of these compounds were evaluated.
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title Synthesis of Some New Heterocycles Derived from Ethyl 7‐Amino‐3‐(3‐methyl‐5‐oxo‐1‐phenyl‐2‐pyrazolin‐4‐yl)‐5‐aryl‐5 H ‐thiazolo[3,2‐ a ]pyrimidine‐6‐carboxylate of Biological Importance
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