Microwave assisted synthesis of thiazolo[3,2-b][1,2,4]-triazoles containing 1,8-naphthyridine moiety

Microwave assisted synthesis of thiazolo[3,2-b][1,2,4]-triazoles containing 1,8-naphthyridine moiety

A simple and efficient protocol for the synthesis of 5‐aryl‐2‐(2‐substituted‐1,8‐naphthyridin‐3‐yl)‐thiazolo[3,2‐b][1,2,4]triazoles (4) is achieved by cyclocondensation of 3‐(2‐substituted‐1,8‐naphthyridin‐3‐yl)‐1,2,4‐triazoles (3) with α‐halogenoketones in anhyd. methanol under microwave irradiatio...

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Veröffentlicht in:Journal of heterocyclic chemistry 2007-09, Vol.44 (5), p.1161-1163
Hauptverfasser: Mogilaiah, K., Prashanthi, M., Kavitha, S., Babu, H. Sharath
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container_issue 5
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container_title Journal of heterocyclic chemistry
container_volume 44
creator Mogilaiah, K.
Prashanthi, M.
Kavitha, S.
Babu, H. Sharath
description A simple and efficient protocol for the synthesis of 5‐aryl‐2‐(2‐substituted‐1,8‐naphthyridin‐3‐yl)‐thiazolo[3,2‐b][1,2,4]triazoles (4) is achieved by cyclocondensation of 3‐(2‐substituted‐1,8‐naphthyridin‐3‐yl)‐1,2,4‐triazoles (3) with α‐halogenoketones in anhyd. methanol under microwave irradiation. The products are obtained in good yields and in a state of high purity.
doi_str_mv 10.1002/jhet.5570440530
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title Microwave assisted synthesis of thiazolo[3,2-b][1,2,4]-triazoles containing 1,8-naphthyridine moiety
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