N-bromosuccinimide reactions of some heterocycles in the presence or absence of water: An overview of ring versus side chain bromination for the synthesis of important brominated heterocyclic synthons

Reactions of various heterocycles 1–6 with N‐bromosuccinimide in the presence or absence of water have been studied for side chain versus ring bromination to afford some new and important heterocyclic synthons. Interestingly, the N‐bromosuccinimide reaction in the presence of perchloric acid, a new...

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Veröffentlicht in:Journal of heterocyclic chemistry 2001-01, Vol.38 (1), p.173-178
Hauptverfasser: Goswami, Shyamaprosad, Ghosh, Kumaresh, Mukherjee, Reshmi, Adak, Avijit Kumar, Mahapatra, Ajit Kumar
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container_end_page 178
container_issue 1
container_start_page 173
container_title Journal of heterocyclic chemistry
container_volume 38
creator Goswami, Shyamaprosad
Ghosh, Kumaresh
Mukherjee, Reshmi
Adak, Avijit Kumar
Mahapatra, Ajit Kumar
description Reactions of various heterocycles 1–6 with N‐bromosuccinimide in the presence or absence of water have been studied for side chain versus ring bromination to afford some new and important heterocyclic synthons. Interestingly, the N‐bromosuccinimide reaction in the presence of perchloric acid, a new condition, affords exclusively the new dibromo aminopicoline 1f, which is not obtained by other presently studied methods.
doi_str_mv 10.1002/jhet.5570380125
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title N-bromosuccinimide reactions of some heterocycles in the presence or absence of water: An overview of ring versus side chain bromination for the synthesis of important brominated heterocyclic synthons
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