Synthesis of novel pyrido[3,4‐d]pyrimidine‐thiazolidione‐1,2,4‐oxadiazoles as potent EGFR targeting anticancer agents

In this study, we designed and synthesized a number of novel pyrido[3,4‐d]pyrimidine‐thiazolidine‐1,2,4‐oxadiazole derivatives and investigated them in vitro for their inhibitory action toward epidermal growth factor receptor (EGFR) kinases and antiproliferative activity against two different cell l...

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Veröffentlicht in:Journal of heterocyclic chemistry 2024-08, Vol.61 (8), p.1314-1324
Hauptverfasser: Varaprasadu, Botla Durga, Haridasyam, Sharath Babu, Koppula, Shiva Kumar
Format: Artikel
Sprache:eng
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