Light, metal‐free regioselective C 6 ‐H alkylation of purines and purine nucleosides with alcohols

A metal‐, light‐free radical alkylation reaction of purines and nucleosides has been achieved with readily available alcohols (1°, 2°, 3°) as the alkyl radical sources enabled by oxalates, which does not need any catalysts, N 2 protection, and protecting groups. Although there are three potential ac...

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Veröffentlicht in:Journal of heterocyclic chemistry 2023-07, Vol.60 (7), p.1179-1189
Hauptverfasser: Liu, Xiguang, Sun, Xiangbin, Wang, Weili, Tian, Miao, Chen, Yiwen, Zou, Chunhui, Yu, Mingwu
Format: Artikel
Sprache:eng
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