Synthesis of 2,5,7‐Triaryl‐4,7(6,7)‐dihydropyrazolo[1,5‐ a ]pyrimidine‐3‐carbonitriles by Reaction of 5(3)‐Amino‐3(5)‐aryl‐1 H ‐pyrazole‐4‐carbonitriles with Chalcones
The reaction of 5(3)‐amino‐3(5)‐aryl‐1 H ‐pyrazole‐4‐carbonitriles with 1,3‐diaryl‐2‐propen‐1‐ones (chalcones) in refluxing DMF leads to 2,5,7‐triaryl‐4,7(6,7)‐dihydropyrazolo[1,5‐ a ]pyrimidine‐3‐carbonitriles. In DMSO solution, the latter exist in equilibrium of two tautomeric 4,7‐dihydropyrazolo[...
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| Veröffentlicht in: | Journal of heterocyclic chemistry 2014-08, Vol.51 (S1) |
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| container_title | Journal of heterocyclic chemistry |
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| creator | Kolosov, Maksim A. Beloborodov, Dmitriy A. Kulyk, Olesia G. Orlov, Valeriy D. |
| description | The reaction of 5(3)‐amino‐3(5)‐aryl‐1
H
‐pyrazole‐4‐carbonitriles with 1,3‐diaryl‐2‐propen‐1‐ones (chalcones) in refluxing DMF leads to 2,5,7‐triaryl‐4,7(6,7)‐dihydropyrazolo[1,5‐
a
]pyrimidine‐3‐carbonitriles. In DMSO solution, the latter exist in equilibrium of two tautomeric 4,7‐dihydropyrazolo[1,5‐
a
]pyrimidines and 6,7‐dihydropyrazolo[1,5‐
a
]pyrimidines in various ratios, depending on the nature of aryl substituents in chalcone building blocks. |
| doi_str_mv | 10.1002/jhet.1824 |
| format | Article |
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H
‐pyrazole‐4‐carbonitriles with 1,3‐diaryl‐2‐propen‐1‐ones (chalcones) in refluxing DMF leads to 2,5,7‐triaryl‐4,7(6,7)‐dihydropyrazolo[1,5‐
a
]pyrimidine‐3‐carbonitriles. In DMSO solution, the latter exist in equilibrium of two tautomeric 4,7‐dihydropyrazolo[1,5‐
a
]pyrimidines and 6,7‐dihydropyrazolo[1,5‐
a
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H
‐pyrazole‐4‐carbonitriles with 1,3‐diaryl‐2‐propen‐1‐ones (chalcones) in refluxing DMF leads to 2,5,7‐triaryl‐4,7(6,7)‐dihydropyrazolo[1,5‐
a
]pyrimidine‐3‐carbonitriles. In DMSO solution, the latter exist in equilibrium of two tautomeric 4,7‐dihydropyrazolo[1,5‐
a
]pyrimidines and 6,7‐dihydropyrazolo[1,5‐
a
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H
‐pyrazole‐4‐carbonitriles with 1,3‐diaryl‐2‐propen‐1‐ones (chalcones) in refluxing DMF leads to 2,5,7‐triaryl‐4,7(6,7)‐dihydropyrazolo[1,5‐
a
]pyrimidine‐3‐carbonitriles. In DMSO solution, the latter exist in equilibrium of two tautomeric 4,7‐dihydropyrazolo[1,5‐
a
]pyrimidines and 6,7‐dihydropyrazolo[1,5‐
a
]pyrimidines in various ratios, depending on the nature of aryl substituents in chalcone building blocks.</abstract><doi>10.1002/jhet.1824</doi></addata></record> |
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| ispartof | Journal of heterocyclic chemistry, 2014-08, Vol.51 (S1) |
| issn | 0022-152X 1943-5193 |
| language | eng |
| recordid | cdi_crossref_primary_10_1002_jhet_1824 |
| source | Access via Wiley Online Library |
| title | Synthesis of 2,5,7‐Triaryl‐4,7(6,7)‐dihydropyrazolo[1,5‐ a ]pyrimidine‐3‐carbonitriles by Reaction of 5(3)‐Amino‐3(5)‐aryl‐1 H ‐pyrazole‐4‐carbonitriles with Chalcones |
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