Population Pharmacokinetics and Dosing Optimization of Amoxicillin in Chinese Infants

Amoxicillin is used to treat various bacterial infections (eg, pneumonia, sepsis, meningitis) in infants. Despite its frequent use, there is a lack of population pharmacokinetic studies in infants, resulting in a substantial variability in dosing regimens used in clinical practice. Therefore, the ob...

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Veröffentlicht in:	Journal of clinical pharmacology 2021-04, Vol.61 (4), p.538-546
Hauptverfasser:	Wu, Yue‐E, Wang, Ya‐Kun, Tang, Bo‐Hao, Dong, Lei, Li, Xue, Zhang, Wei, Li, Di‐Fei, Tian, Li‐Yuan, den Anker, John, You, Dian‐Ping, Zhao, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	amoxicillin Amoxicillin - pharmacokinetics Amoxicillin - pharmacology Anti-Bacterial Agents - pharmacokinetics Anti-Bacterial Agents - pharmacology bacterial infections Computer Simulation dosing optimization Humans Infant infants Microbial Sensitivity Tests Models, Biological Monte Carlo Method population pharmacokinetics
Online-Zugang:	Volltext
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