β 2 -Adrenergic Receptor Gene Affects the Heart Rate Response of β-Blockers: Evidence From 3 Clinical Studies

β-Blockers' heart rate (HR)-lowering effect is an important determinant of the effectiveness for this class of drugs, yet it is variable among β-blocker-treated patients. To date, genetic studies have revealed several genetic signals associated with HR response to β-blockers. However, these gen...

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Veröffentlicht in:	Journal of clinical pharmacology 2019-11, Vol.59 (11), p.1462-1470
Hauptverfasser:	Shahin, Mohamed H, Rouby, Nihal El, Conrado, Daniela J, Gonzalez, Daniel, Gong, Yan, Lobmeyer, Maximilian T, Beitelshees, Amber L, Boerwinkle, Eric, Gums, John G, Chapman, Arlene, Turner, Stephen T, Pepine, Carl J, Cooper-DeHoff, Rhonda M, Johnson, Julie A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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