Adiponectin increases BMP-2 expression in osteoblasts via AdipoR receptor signaling pathway

Adiponectin is a protein hormone secreted predominantly by differentiated adipocytes and involved in energy homeostasis. Bone morphogenetic protein (BMP) plays important roles in osteoblastic differentiation and bone formation. However, the effects of adiponectin on BMPs expression in cultured osteo...

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Veröffentlicht in:	Journal of cellular physiology 2010-08, Vol.224 (2), p.475-483
Hauptverfasser:	Huang, Chun-Yin, Lee, Chun-Yi, Chen, Meng-Yi, Tsai, Hsiao-Chi, Hsu, Horng-Chaung, Tang, Chih-Hsin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin - pharmacology AMP-Activated Protein Kinases - metabolism Animals Bone Morphogenetic Protein 2 - genetics Bone Morphogenetic Protein 2 - metabolism Cell Line Gene Expression Regulation - drug effects Humans Mice NF-kappa B - metabolism Osteoblasts - drug effects Osteoblasts - enzymology Osteoblasts - metabolism p38 Mitogen-Activated Protein Kinases - metabolism Receptors, Adiponectin - metabolism Signal Transduction - drug effects
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