The non-genomic effects on Na+/H+-exchange 1 by progesterone and 20α-hydroxyprogesterone in human T cells

Progesterone is an endogenous immunomodulator and can suppress T‐cell activation during pregnancy. We have previously shown that the non‐genomic effects of progesterone, especially acidification, are exerted via plasma membrane sites and suppress cellular genomic responses to mitogens. This study ai...

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Veröffentlicht in:Journal of cellular physiology 2007-05, Vol.211 (2), p.544-550
Hauptverfasser: Chien, Eileen Jea, Liao, Ching-Fong, Chang, Ching-Pang, Pu, Hsiao-Fung, Lu, Li-Ming, Shie, Mei-Chi, Hsieh, Dennis J.-Y., Hsu, Ming-Ta
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Sprache:eng
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