The class II phosphoinositide 3-kinase PI3K-C2β regulates cell migration by a PtdIns(3)P dependent mechanism

The biological and pathophysiological significance of class II phosphoinositide 3‐kinase enzyme expression currently remains unclear. Using an in vitro scrape wound assay and time‐lapse video microscopy, we demonstrate that cell motility is increased in cultures expressing recombinant PI3K‐C2β enzym...

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Veröffentlicht in:	Journal of cellular physiology 2005-12, Vol.205 (3), p.452-462
Hauptverfasser:	Domin, Jan, Harper, Lisa, Aubyn, Deborah, Wheeler, Matthew, Florey, Oliver, Haskard, Dorian, Yuan, Ming, Zicha, Daniel
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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