Role of Ca 2+ in stimulation of DNA synthesis by epidermal growth factor and tumor promoters in cultured rat hepatocytes

This study examines the effects of extracellular Ca 2+ concentrations, [Ca 2+ ] o , and of treatments known to modulate intracellular Ca 2+ levels on the extent and timing of DNA synthesis in primary cultures of adult rat hepatocytes. In cultures exposed to insulin and EGF, the extent of DNA synthes...

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Veröffentlicht in:Journal of cellular physiology 1993-04, Vol.155 (1), p.44-53
Hauptverfasser: Petronijevic, Tadija, Edwards, Anthony M.
Format: Artikel
Sprache:eng
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