Concise Synthesis and Antimicrobial Activities of New Substituted 5-Isoxazolpenicillins

The synthesis of a series of new 5‐isoxazolpenicillins is described, which were obtained by coupling substituted isoxazoles with 6‐APA. Concise large‐scale synthesis of 3,5‐disubstituted isoxazoles by 1,3‐dipolar cycloaddition using copper(I) as catalyst was also investigated. Representative compoun...

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Veröffentlicht in:	Journal of the Chinese Chemical Society (Taipei) 2007-06, Vol.54 (3), p.643-652
Hauptverfasser:	Wang, Xi-Zhao, Jia, Jiong, Zhang, Yan, Xu, Wei-Ren, Liu, Wei, Shi, Fang-Niu, Wang, Jian-Wu
Format:	Artikel
Sprache:	eng
Schlagworte:	Antimicrobial activity Isoxazole Penicillin Synthesis
Online-Zugang:	Volltext
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