Streptococcus mutans GS-5 antigen I/II stimulates cell survival in serum deprived-cultures through PI3K/Akt Pathways

The antigen I/II (AgI/II) protein is a major surface protein that mediates the attachment of Streptococcus mutans (S. mutans) to the saliva‐coated pellicle. Numerous studies have investigated not only the mechanisms by which AgI/II signaling is transduced within cells, but have also attempted to use...

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Veröffentlicht in:	Journal of cellular biochemistry 2012-05, Vol.113 (5), p.1724-1732
Hauptverfasser:	Son, Young-Ok, Jeon, Young-Mi, Kim, Yu-Shin, Park, Soon-Sun, Park, Seung-Moon, Kim, Ji-Hae, Lee, Jeong-Chae
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Bacterial - administration & dosage Antigens, Bacterial - physiology Bacterial Proteins - administration & dosage Bacterial Proteins - immunology CALVARIAL OSTEOBLASTS Cell Cycle CELL CYCLE PROGRESSION Cell Proliferation Cell Survival - immunology Cells, Cultured Culture Media, Serum-Free Host-Pathogen Interactions - immunology Mice Mitochondria - metabolism Models, Biological Osteoblasts - immunology Osteoblasts - metabolism Osteoblasts - microbiology Osteoblasts - pathology Phosphatidylinositol 3-Kinases - metabolism Proto-Oncogene Proteins c-akt - metabolism RECOMBINANT AgI/II Recombinant Proteins - administration & dosage Recombinant Proteins - immunology Signal Transduction SIGNAL TRANSDUCTION PATHWAYS Streptococcus mutans - immunology Streptococcus mutans - pathogenicity Stress, Physiological SURVIVAL
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