C‐kit mutations and PKC crosstalks: PKC translocates to nucleous only in cells HMC 560,816

The human mast cell lines HMC‐1 560 and HMC‐1 560,816 were used to study histamine release, Ca 2+ signaling and protein kinase C (PKC) localization and expression, with phorbol 12‐myristate 13‐acetate (PMA). Both sublines carry activating mutations in the proto‐oncogene of c‐kit that cause autophosp...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of cellular biochemistry 2011-09, Vol.112 (9), p.2637-2651
Hauptverfasser:	Tobío, Araceli, Alfonso, Amparo, Botana, Luis M.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!