Tranferrins receptor association and endosomal localization of soluble HFE are not sufficient for regulation of cellular iron homeostasis

Iron uptake and storage are tightly regulated to guarantee sufficient iron for essential cellular processes and to prevent the production of damaging free radicals. A non‐classical class I MHC molecule, the hemochromatosis factor HFE, has been shown to regulate iron metabolism, potentially via its d...

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Veröffentlicht in:	Journal of cellular biochemistry 2004-04, Vol.91 (6), p.1130-1145
Hauptverfasser:	Laham, Nihay, Rotem-Yehudar, Rinat, Shechter, Chana, Coligan, John E., Ehrlich, Rachel
Format:	Artikel
Sprache:	eng
Schlagworte:	hemochromatosis Hfe iron metabolism TfR trafficking
Online-Zugang:	Volltext
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