Transcriptional regulation of Smad2 is required for enhancement of TGFβ/Smad signaling by TGFβ inducible early gene

TGFβ inducible early gene (TIEG) is a novel Krüppel‐like transcriptional repressor that was recently shown to increase the activity of the TGFβ/Smad signal transduction pathway by relieving negative feedback through repression of the inhibitory Smad7. Interestingly, while Smad7 is required for maxim...

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Veröffentlicht in:	Journal of cellular biochemistry 2002, Vol.87 (2), p.233-241
Hauptverfasser:	Johnsen, Steven A., Subramaniam, Malayannan, Katagiri, Takenobu, Janknecht, Ralf, Spelsberg, Thomas C.
Format:	Artikel
Sprache:	eng
Schlagworte:	bone morphogenetic protein (BMP) Krüppel-like factor (KLF) Smad TGFβ inducible early gene (TIEG) transforming growth factor-β (TGFβ)
Online-Zugang:	Volltext
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