Current practices in generation of small molecule new leads

The current drug discovery processes in many pharmaceutical companies require large and growing collections of high quality lead structures for use in high throughput screening assays. Collections of small molecules with diverse structures and “drug‐like” properties have, in the past, been acquired...

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Veröffentlicht in:	Journal of cellular biochemistry 2001, Vol.84 (S37), p.13-21
1. Verfasser:	Goodnow Jr, Robert A.
Format:	Artikel
Sprache:	eng
Schlagworte:	chemical genomics Chemistry, Pharmaceutical Combinatorial Chemistry Techniques Drug Delivery Systems Drug Design drug-likeness high-throughput chemistry lead generation lead-likeness Structure-Activity Relationship
Online-Zugang:	Volltext
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