Effect of phenobarbital and the peroxisome proliferator ciprofibrate on γ‐glutamyltranspeptidase activity and leukotriene C 4 concentration in cultured rat hepatocytes

Peroxisome proliferators induce hepatocellular carcinomas in rodents by an unknown mechanism. γ‐Glutamyltranspeptidase (GGT), a biochemical marker for identifying putative preneoplastic lesions in the liver, is highly expressed in phenobarbital (PB)‐promoted altered hepatic foci but not in those pro...

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Veröffentlicht in:Journal of biochemical toxicology 1995-10, Vol.10 (5), p.239-243
Hauptverfasser: Hong, Jin T., Wilson, Mary W., Glauert, Howard P.
Format: Artikel
Sprache:eng
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