Effect of donor age on the levels of activity of rat, hamster and human liver S9 preparations in the Salmonella mutagenicity assay

Liver S9 fractions were prepared from male and female Syrian Golden hamsters and Sprague‐Dawley rats, 1, 3, 6 and 12 months of age, which were either iuninduced (corn‐oil treated) or induced with Aroclor 1254 suspended in corn oil. These preparations were compared at varying protein levels for their...

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Veröffentlicht in:	Journal of applied toxicology 1986-04, Vol.6 (2), p.101-108
Hauptverfasser:	Raineri, R., Andrews, A. W., Poiley, J. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Acetylaminofluorene - metabolism Age Factors Aged Animals Biological and medical sciences Chemical mutagenesis Cricetinae donor age Female hamster human Humans Liver - metabolism Male Medical sciences Mesocricetus Middle Aged mutagenicity Mutagenicity Tests Mutagens - metabolism Nitrosamines - metabolism Polycyclic Compounds - metabolism rat Rats Rats, Inbred Strains S9, donor age Salmonella - drug effects Species Specificity Toxicology
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