Nalidixic acid and oxolinic acid reversibly suppress 3‐methylcholanthrene‐induced cell transformation of BALB/3T3 mouse cells

The effects of nalidixic acid (Nal) and oxolinic acid (Oxl), synthetic antibacterial compounds that inhibit bacterial DNA gyrase, on 3‐methylcholanthrene (MC)‐induced transformation of BALB/3T3 mouse cells were investigated. Exposure of the cells to Nal or Oxl for 2 weeks at any time during 4 weeks...

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Veröffentlicht in:	International journal of cancer 1988-12, Vol.42 (6), p.913-916
Hauptverfasser:	Kaneko, Motohisa, Horikoshi, Junko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Cell Communication - drug effects Cell physiology Cell Transformation, Neoplastic - drug effects Cells, Cultured Fundamental and applied biological sciences. Psychology Methylcholanthrene Mice Molecular and cellular biology Nalidixic Acid - pharmacology Oxolinic Acid - pharmacology Tetradecanoylphorbol Acetate Transcription, Genetic - drug effects
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