Antagonistic action of retinoic acid and teleocidin on the proliferation and epidermal growth factor binding of rat hepatoma cells

Rat hepatoma cells were cultured in a medium with suboptimal concentration of fetal calf serum. In this low serum culture, retinoic acid inhibited the cell proliferation and enhanced the number of receptors for epidermal growth factor (EGF). On the contrary, teleocidin, a possible naturally occurrin...

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Veröffentlicht in:	International journal of cancer 1981-06, Vol.27 (6), p.841-846
1. Verfasser:	Kaneko, Yoshiyasu
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - pharmacology Animals Cell Division - drug effects Cells, Cultured Epidermis - metabolism Glycoproteins - biosynthesis Growth Substances - metabolism Liver Neoplasms, Experimental - drug therapy Liver Neoplasms, Experimental - metabolism Liver Neoplasms, Experimental - pathology Lyngbya Toxins Rats Receptors, Drug - drug effects Tretinoin - pharmacology
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