The reduction of cell death and proliferation by p27 Kip1 minimizes DNA damage in an experimental model of genotoxicity

Hepatocellular carcinoma (HCC) is the fifth most commonly occurring cancer worldwide. The expression of p27 has been related to reduced severity of tumor grade and recurrence of HCC. The study assessed the role of p27 on the cell proliferation and death, and DNA mutagenesis in experimental genotoxic...

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Veröffentlicht in:International journal of cancer 2009-11, Vol.125 (10), p.2270-2280
Hauptverfasser: Ranchal, Isidora, González, Raúl, Bello, Rosario I., Ferrín, Gustavo, Hidalgo, Ana B., Linares, Clara I., Aguilar‐Melero, Patricia, González‐Rubio, Sandra, Barrera, Pilar, Marchal, Trinidad, Nakayama, Keiichi I., de la Mata, Manuel, Muntané, Jordi
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Sprache:eng
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