Expression of xenobiotic and steroid hormone metabolizing enzymes in human breast carcinomas

The potential to metabolize endogenous and exogenous substances may influence breast cancer development and tumor growth. Therefore, the authors investigated the protein expression of Glutathione S‐transferase (GST) isoforms and cytochrome P450 (CYP) known to be involved in the metabolism of steroid...

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Veröffentlicht in:	International journal of cancer 2006-10, Vol.119 (8), p.1785-1791
Hauptverfasser:	Haas, Susanne, Pierl, Christiane, Harth, Volker, Pesch, Beate, Rabstein, Sylvia, Brüning, Thomas, Ko, Yon, Hamann, Ute, Justenhoven, Christina, Brauch, Hiltrud, Fischer, Hans‐Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences breast carcinoma Breast Neoplasms - classification Breast Neoplasms - enzymology Breast Neoplasms - metabolism Breast Neoplasms - pathology CYP Cytochrome P-450 Enzyme System - metabolism estrogen receptor Glutathione Transferase - metabolism GST Gynecology. Andrology. Obstetrics Hormones - metabolism Humans immunohistochemistry Mammary gland diseases Medical sciences Middle Aged progesterone receptor Receptor, ErbB-2 - metabolism Steroids - metabolism Tumor Suppressor Protein p53 - metabolism Tumors Ubiquitin-Protein Ligases - metabolism Xenobiotics - metabolism
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