Antiangiogenic combination tumor therapy blocking αv‐integrins and VEGF‐receptor‐2 increases therapeutic effects in vivo

Anti‐angiogenesis is a promising strategy for cancer therapy currently evaluated in clinical trials. The aim of the study was to investigate the effects of an antiangiogenic combination therapy inhibiting αv‐integrins by a c(yclic)RGD‐peptide (EMD270179) and blocking VEGFR‐2 by SU5416 on tumor angio...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of cancer 2006-07, Vol.119 (2), p.423-431
Hauptverfasser:	Strieth, Sebastian, Eichhorn, Martin E., Sutter, Arne, Jonczyk, Alfred, Berghaus, Alexander, Dellian, Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	antiangiogenic combination therapy Antineoplastic agents Biological and medical sciences Chemotherapy intravital microscopy Medical sciences Pharmacology. Drug treatments RGD SU5416 tumor microcirculation Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!