Overexpression of hypoxia‐inducible factor HIF‐1α predicts early relapse in breast cancer: Retrospective study in a series of 745 patients

Hypoxia‐inducible factor‐1α (HIF‐1α) is a transcription factor that is involved in tumour growth and metastasis by regulating genes involved in response to hypoxia. HIF‐1α protein overexpression has been shown in a variety of human cancers, but only 2 studies have documented the prognostic relevance...

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Veröffentlicht in:International journal of cancer 2005-09, Vol.116 (5), p.734-739
Hauptverfasser: Dales, Jean‐Philippe, Garcia, Stéphane, Meunier‐Carpentier, Séverine, Andrac‐Meyer, Lucile, Haddad, Olivier, Lavaut, Marie‐Noölle, Allasia, Claude, Bonnier, Pascal, Charpin, Colette
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Sprache:eng
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