Stereoselective binding of 11 C‐labelled piquindone (Ro 22–1319) to dopamine‐D2 receptors in the living human brain

The stereoenantiomers of piquindone (Ro 22–1319), a new antipsychotic pyrroloisoquinoline derivative, were labelled with the positron‐emitting isotope 11 C. Only the (−)‐enantiomer inherits most of the biological activity of racemic piquindone. The compounds were examined by positron emission tomogr...

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Veröffentlicht in:	Human psychopharmacology 1987-03, Vol.2 (1), p.23-30
Hauptverfasser:	Sedvall, G., Ehrin, E., Farde, L.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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