Saccadic peak velocity and EEG as end-points for a serotonergic challenge test

We previously reported that a single dose of the serotonin receptor agonist meta‐chlorophenylpiperazine increased the peak velocity of saccadic eye movements and decreased low‐frequency electroencephalographic activity. Methods We administered a single dose of the serotonin releaser dexfenfluramine...

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Veröffentlicht in:	Human psychopharmacology 2002-03, Vol.17 (2), p.83-89
Hauptverfasser:	Gijsman, Harm J., van Gerven, Joop M. A., Verkes, Robbert Jan, Schoemaker, Rik C., Pieters, Monique S. M., Pennings, Ed J. M., Hessing, Trees J., Cohen, Adam F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Cross-Over Studies dexfenfluramine Dexfenfluramine - pharmacokinetics Dexfenfluramine - pharmacology Dose-Response Relationship, Drug Double-Blind Method ecstasy EEG Electroencephalography Hallucinogens Humans Male MDMA N-Methyl-3,4-methylenedioxyamphetamine Norfenfluramine - metabolism pharmacodynamics pharmacokinetics PKPD Saccades - drug effects saccadic eye movements serotonin Serotonin - physiology Serotonin Receptor Agonists - pharmacokinetics Serotonin Receptor Agonists - pharmacology Substance-Related Disorders - physiopathology
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