A randomized trial of continuous infusion versus bolus mitoxantrone in combination with cytarabine in newly diagnosed patients with acute myeloblastic leukemia

Mitoxantrone (MTZ) has been shown to be effective in the treatment of newly diagnosed acute myeloblastic leukemia (AML). The objective of this randomized study was to evaluate the impact of mode of administration of MTZ on the response and recurrence rates in newly diagnosed patients with AML and to...

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Veröffentlicht in:	Hematological oncology 2004-06, Vol.22 (2), p.43-53
Hauptverfasser:	Koc, Yener, Oyan, Basak, Kars, Ayse, Tekuzman, Gulten, Canpinar, Hande, Kansu, Emin
Format:	Artikel
Sprache:	eng
Schlagworte:	acute myeloblastic leukemia Adolescent Adult Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use continuous infusion Cytarabine - administration & dosage Disease-Free Survival Female Humans Leukemia, Myeloid, Acute - drug therapy Male Middle Aged mitoxantrone Mitoxantrone - administration & dosage Remission Induction survival Time Factors Treatment Outcome
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