Isoprenoids and Flavonoids with Antimicrobial Activity from Ficus conraui Warburg (Moraceae)
A new triterpene, conrauidienol (1), and a new dihydroflavonol, conrauiflavonol (2), along with β‐amyrin acetate (3), betulinic acid (4), ursolic acid (5), 6β‐hydroxystigmasta‐4,22‐dien‐3‐one (6), 8‐prenylapigenin (7), β‐sitosterol glucoside (8), and 3,4′,5‐trihydroxy‐6″,6″‐dimethylpyrano[2,3‐g]flav...
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| Veröffentlicht in: | Helvetica chimica acta 2011-12, Vol.94 (12), p.2231-2238 |
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| creator | Kengap, Rodrigue T. Kapche, Gilbert D. W. F. Dzoyem, Jean-Paul Simo, Ingrid K. Ambassa, Pantaleon Sandjo, Louis P. Abegaz, Berhanu M. Ngadjui, Bonaventure T. |
| description | A new triterpene, conrauidienol (1), and a new dihydroflavonol, conrauiflavonol (2), along with β‐amyrin acetate (3), betulinic acid (4), ursolic acid (5), 6β‐hydroxystigmasta‐4,22‐dien‐3‐one (6), 8‐prenylapigenin (7), β‐sitosterol glucoside (8), and 3,4′,5‐trihydroxy‐6″,6″‐dimethylpyrano[2,3‐g]flavone (9) were isolated from the stem barks of Ficus conraui Warburg (Moraceae). Their structures were elucidated by spectroscopic analysis. The hexane, AcOEt, and MeOH extracts, as well as the new isolated compounds exhibited selective antimicrobial activities varying from weak to moderate. |
| doi_str_mv | 10.1002/hlca.201100173 |
| format | Article |
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W. F. ; Dzoyem, Jean-Paul ; Simo, Ingrid K. ; Ambassa, Pantaleon ; Sandjo, Louis P. ; Abegaz, Berhanu M. ; Ngadjui, Bonaventure T.</creator><creatorcontrib>Kengap, Rodrigue T. ; Kapche, Gilbert D. W. F. ; Dzoyem, Jean-Paul ; Simo, Ingrid K. ; Ambassa, Pantaleon ; Sandjo, Louis P. ; Abegaz, Berhanu M. ; Ngadjui, Bonaventure T.</creatorcontrib><description>A new triterpene, conrauidienol (1), and a new dihydroflavonol, conrauiflavonol (2), along with β‐amyrin acetate (3), betulinic acid (4), ursolic acid (5), 6β‐hydroxystigmasta‐4,22‐dien‐3‐one (6), 8‐prenylapigenin (7), β‐sitosterol glucoside (8), and 3,4′,5‐trihydroxy‐6″,6″‐dimethylpyrano[2,3‐g]flavone (9) were isolated from the stem barks of Ficus conraui Warburg (Moraceae). Their structures were elucidated by spectroscopic analysis. The hexane, AcOEt, and MeOH extracts, as well as the new isolated compounds exhibited selective antimicrobial activities varying from weak to moderate.</description><identifier>ISSN: 0018-019X</identifier><identifier>EISSN: 1522-2675</identifier><identifier>DOI: 10.1002/hlca.201100173</identifier><language>eng</language><publisher>Zürich: WILEY-VCH Verlag</publisher><subject>Antimicrobial activity ; Conrauidienol ; Conrauiflavonol ; dihydro ; Ficus conraui ; Flavonol ; Flavonol, dihydro ; Triterpenes</subject><ispartof>Helvetica chimica acta, 2011-12, Vol.94 (12), p.2231-2238</ispartof><rights>Copyright © 2011 Verlag Helvetica Chimica Acta AG, Zürich, Switzerland</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3273-3933d1de9300228e51a792eb3abdbb00b0ca1ff2a2c48203af3eeef2a860efcc3</citedby><cites>FETCH-LOGICAL-c3273-3933d1de9300228e51a792eb3abdbb00b0ca1ff2a2c48203af3eeef2a860efcc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fhlca.201100173$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fhlca.201100173$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids></links><search><creatorcontrib>Kengap, Rodrigue T.</creatorcontrib><creatorcontrib>Kapche, Gilbert D. 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The hexane, AcOEt, and MeOH extracts, as well as the new isolated compounds exhibited selective antimicrobial activities varying from weak to moderate.</description><subject>Antimicrobial activity</subject><subject>Conrauidienol</subject><subject>Conrauiflavonol</subject><subject>dihydro</subject><subject>Ficus conraui</subject><subject>Flavonol</subject><subject>Flavonol, dihydro</subject><subject>Triterpenes</subject><issn>0018-019X</issn><issn>1522-2675</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNqFkE1PwzAMhiMEEmNw5ZwjHFqcZF3bY1WxDzHgAgwhpMhNUxbo2inpNvbv6VQ0ceNkvZYfy34IuWTgMwB-sygV-hxYG1gojkiPBZx7fBgGx6TX9iIPWPx6Ss6c-wSAOIawR96nrl5ZXdUmdxSrnI5K3NRd3JpmQZOqMUujbJ0ZLGmiGrMxzY4Wtl7SkVFrR1VdWVwbOkebre0HvbqvLSqN-vqcnBRYOn3xW_vkeXT7lE682eN4miYzTwkeCk_EQuQs17Fo3-CRDhiGMdeZwCzPMoAMFLKi4MjVIOIgsBBa6zZHQ9CFUqJP_G5ve6ZzVhdyZc0S7U4ykHs3cu9GHty0QNwBW1Pq3T_TcjJLk7-s17HGNfr7wKL9ksNQhIGcP4wluxukUfQyl2_iB9-heVg</recordid><startdate>201112</startdate><enddate>201112</enddate><creator>Kengap, Rodrigue T.</creator><creator>Kapche, Gilbert D. 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F.</creatorcontrib><creatorcontrib>Dzoyem, Jean-Paul</creatorcontrib><creatorcontrib>Simo, Ingrid K.</creatorcontrib><creatorcontrib>Ambassa, Pantaleon</creatorcontrib><creatorcontrib>Sandjo, Louis P.</creatorcontrib><creatorcontrib>Abegaz, Berhanu M.</creatorcontrib><creatorcontrib>Ngadjui, Bonaventure T.</creatorcontrib><collection>Istex</collection><collection>CrossRef</collection><jtitle>Helvetica chimica acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kengap, Rodrigue T.</au><au>Kapche, Gilbert D. W. F.</au><au>Dzoyem, Jean-Paul</au><au>Simo, Ingrid K.</au><au>Ambassa, Pantaleon</au><au>Sandjo, Louis P.</au><au>Abegaz, Berhanu M.</au><au>Ngadjui, Bonaventure T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Isoprenoids and Flavonoids with Antimicrobial Activity from Ficus conraui Warburg (Moraceae)</atitle><jtitle>Helvetica chimica acta</jtitle><addtitle>HCA</addtitle><date>2011-12</date><risdate>2011</risdate><volume>94</volume><issue>12</issue><spage>2231</spage><epage>2238</epage><pages>2231-2238</pages><issn>0018-019X</issn><eissn>1522-2675</eissn><abstract>A new triterpene, conrauidienol (1), and a new dihydroflavonol, conrauiflavonol (2), along with β‐amyrin acetate (3), betulinic acid (4), ursolic acid (5), 6β‐hydroxystigmasta‐4,22‐dien‐3‐one (6), 8‐prenylapigenin (7), β‐sitosterol glucoside (8), and 3,4′,5‐trihydroxy‐6″,6″‐dimethylpyrano[2,3‐g]flavone (9) were isolated from the stem barks of Ficus conraui Warburg (Moraceae). Their structures were elucidated by spectroscopic analysis. The hexane, AcOEt, and MeOH extracts, as well as the new isolated compounds exhibited selective antimicrobial activities varying from weak to moderate.</abstract><cop>Zürich</cop><pub>WILEY-VCH Verlag</pub><doi>10.1002/hlca.201100173</doi><tpages>8</tpages></addata></record> |
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| language | eng |
| recordid | cdi_crossref_primary_10_1002_hlca_201100173 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Antimicrobial activity Conrauidienol Conrauiflavonol dihydro Ficus conraui Flavonol Flavonol, dihydro Triterpenes |
| title | Isoprenoids and Flavonoids with Antimicrobial Activity from Ficus conraui Warburg (Moraceae) |
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