Oligonucleotides Containing Consecutive 2′-Deoxyisoguanosine Residues: Synthesis, duplexes with parallel chain orientation, and aggregation

The 2′‐deoxyisoguanosine phosphonates 3a and 4a and the phosphoramidites 3b and 4b were prepared as building blocks for solid‐phase oligonucleotide synthesis. The diphenylcarbamoyl (dpc) residue was introduced as 2‐oxo protecting group which stabilizes the N‐glycosylic bond against hydrolysis and pr...

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Veröffentlicht in:	Helvetica chimica acta 1997-02, Vol.80 (1), p.73-85
Hauptverfasser:	Seela, Frank, Wei, Changfu
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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