Effects of exercise on NMDA receptor subunit contributions to bidirectional synaptic plasticity in the mouse dentate gyrus

We examined synaptic plasticity in the dentate gyrus (DG) of the hippocampus in vitro in juvenile C57Bl6 mice (28–40 days of age), housed in control conditions with minimal enrichment (Controls) or with access to an exercise wheel (Runners). LTP expression was significantly greater in slices from Ru...

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Veröffentlicht in:	Hippocampus 2007-01, Vol.17 (12), p.1201-1208
Hauptverfasser:	Vasuta, Cristina, Caunt, Charlotte, James, Rachel, Samadi, Shervin, Schibuk, Elizabeth, Kannangara, Timal, Titterness, Andrea K., Christie, Brian R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aspartic Acid - pharmacology Behavior, Animal dentate gyrus Dentate Gyrus - cytology Dentate Gyrus - physiology Dose-Response Relationship, Radiation Drug Interactions Electric Stimulation - methods Excitatory Amino Acid Agents - pharmacology exercise In Vitro Techniques LTD LTP Mice Mice, Inbred C57BL Mice, Knockout Neuronal Plasticity - drug effects Neuronal Plasticity - physiology Neuronal Plasticity - radiation effects Neurons - physiology NMDA Physical Conditioning, Animal Piperidines - pharmacology Quinoxalines - pharmacology Receptors, N-Methyl-D-Aspartate - deficiency Receptors, N-Methyl-D-Aspartate - physiology
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