Expression of cyclooxygenase‐2 in human hepatocellular carcinoma: Relevance to tumor dedifferentiation

Cyclooxygenase (rlCOX) is a key enzyme in the synthesis of prostanoids. Two isoforms of this enzyme have been identified: COX‐1 and COX‐2. Recent studies have suggested that COX‐2, but not COX‐1, may play a role in colorectal tumorigenesis. In the present study, we investigated the expression of COX...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 1999-03, Vol.29 (3), p.688-696
Hauptverfasser:	Koga, Hironori, Sakisaka, Shotaro, Ohishi, Masahito, Kawaguchi, Takumi, Taniguchi, Eitaro, Sasatomi, Kurumi, Harada, Masaru, Kusaba, Taku, Tanaka, Masatoshi, Kimura, Rina, Nakashima, Yutaka, Nakashima, Osamu, Kojiro, Masamichi, Kurohiji, Toshihiko, Sata, Michio
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Blotting, Western Carcinoma, Hepatocellular - enzymology Carcinoma, Hepatocellular - pathology Cyclooxygenase 1 Cyclooxygenase 2 Female Gastroenterology. Liver. Pancreas. Abdomen Humans Immunohistochemistry Isoenzymes - metabolism Liver Neoplasms - enzymology Liver Neoplasms - pathology Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Membrane Proteins Middle Aged Prostaglandin-Endoperoxide Synthases - metabolism Tumors
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