Role of sinusoidal endothelial cells of the liver in concanavalin A‐induced hepatic injury in mice

CD4+ T lymphocytes have been identified as being responsible for organ damage in the murine model of experimental liver injury induced by intravenous injection of concanavalin A (Con A). Liver sinusoidal endothelial cells (SEC) and Kupffer's cells (KC) are among the first cells that come into c...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 1996-10, Vol.24 (4), p.824-829
Hauptverfasser:	Knolle, P A, Gerken, G, Löser, E, Dienes, H P, Gantner, F, Tiegs, G, Meyer zum Büschenfelde, K, Lohse, A W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism Concanavalin A - administration & dosage Concanavalin A - metabolism Endothelium - metabolism Female Fibroblasts - immunology Gadolinium - pharmacology Gastroenterology. Liver. Pancreas. Abdomen Hepatic Encephalopathy - chemically induced Hepatic Encephalopathy - immunology Hepatic Encephalopathy - metabolism Hepatic Encephalopathy - pathology Injections, Intravenous Kupffer Cells - drug effects Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Mice Mice, Inbred BALB C Organ Specificity Other diseases. Semiology T-Lymphocytes, Cytotoxic - immunology Tumor Necrosis Factor-alpha - immunology Tumor Necrosis Factor-alpha - metabolism
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