Combined GM‐CSF and IL‐12 gene therapy synergistically suppresses the growth of orthotopic liver tumors

Immunotherapy is often effective only for small tumor burdens and, in many cases, is restricted to subcutaneous tumors. Here, we investigated the antitumor effects of combination therapy with GM‐CSF and IL‐12 on orthotopic liver tumors with intermediate or large tumor volumes, or on chemically‐induc...

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